Subdivision
| • | 204. Medicine, Surgery, Pathology and Immunology | [X] |
| | 1 | Name: | Dr. Robert Austrian | | | Institution: | University of Pennsylvania School of Medicine | | | Year Elected: | 1987 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Deceased
| | | Birth Date: | 1916 | | | Death Date: | March 25, 2007 | | | | |
| 2 | Name: | Dr. Clyde Frederick Barker | | | Institution: | American Philosophical Society; University of Pennsylvania | | | Year Elected: | 1997 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Living
| | | Birth Date: | 1932 | | | | | | |
Clyde F. Barker is a native of Salt Lake City and a graduate of Phillips Exeter Academy, Cornell University, and Cornell University Medical College. His internship and residency in surgery were at the Hospital of the University of Pennsylvania, where he has served his entire academic and professional career. Following residency training he was a fellow in vascular surgery and then a postdoctoral fellow in medical genetics under Rupert Billingham, studying transplantation biology. He was appointed to the faculty of the University of Pennsylvania in 1966 and became Professor of Surgery in 1973. From 1966 to 2001 he was Chief of Transplantation Surgery and, from 1982 to 2001, Chief of the Division of Vascular Surgery. From 1983 to 2001 he was the John Rhea Barton Professor and Chairman of the Department of Surgery, and Director of the Harrison Department of Surgical Research. He is now Donald Guthrie Professor of Surgery. The Clyde F. Barker Transplant House at University of Pennsylvania Hospital is named in his honor.
Clyde Barker’s research interests have been primarily in transplantation, especially transplantation of the kidney and pancreas and of isolated pancreatic islets. His research was continuously funded for more than 25 years by grants from the National Institutes of Health, including an NIH Merit Award from 1987-95. He has published more than 400 scientific papers and has served on 12 editorial boards, including the Journal of Surgical Research, Diabetes, Transplantation, Archives of Surgery, Surgery, Journal of the American College of Surgeons, and The Annals of Surgery.
Clyde Barker is a member of the National Academy of Medicine, American Academy of Arts & Sciences, and the Association of American Physicians. He has been President of the American Society of Transplantation Surgeons, the International Society of Surgery, and the American Surgical Association. He has served as visiting professor at 80 different universities and is an Honorary Fellow of the Royal College of Surgeons of England and of the Royal College of Surgeons in Ireland. He is the recipient of lifetime achievement awards from the American College of Surgeons and the Society of University Surgeons, the 2007 Jonathan E. Rhoads Medal for Distinguished Achievement in Medicine, the Thomas E. Starzl Prize in 2009, and the 2010 Medawar Prize from the Transplantation Society. The Medawar Prize is recognized as the world’s highest award dedicated to the outstanding contributions in the field of transplantation. In 2010 he was awarded the American Philosophical Society’s Henry Allen Moe Prize in the Humanities in recognition of his Jayne Lecture delivered to the members of the Society at its 2007 November Meeting and published in the Society’s Proceedings, March 2009, entitled "Thomas Eakins and His Medical Clinics." Clyde Barker was elected to the American Philosophical Society in 1997 and has served on Council and as a Vice President. He served as the Society’s President from April 2011 through April 2017. | |
| 3 | Name: | Dr. Alexander G. Bearn | | | Institution: | American Philosophical Society | | | Year Elected: | 1972 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Deceased
| | | Birth Date: | 1923 | | | Death Date: | May 15, 2009 | | | | | | |
Alexander G. Bearn was Executive Officer of the American Philosophical Society from 1997 until his retirement in 2002. A physician, scientist and author, Dr. Bearn became a member of the Society in 1972 and served as a vice president from 1988-96. He received the Society's Benjamin Franklin Medal in 2001. The citation read "in recognition of distinguished contributions as a physician and scientist, represented by his service as Stanton Griffis Distinguished Professor and Chairman of the Department of Medicine at Cornell University Medical College and Physician-in-Chief at the New York Hospital, as Senior Vice President for Medical and Scientific Affairs at Merck, Sharp and Dohme and as Editor of the American Journal of Medicine. The Society places on record its profound appreciation for his outstanding service, wise leadership and exemplary devotion to the life and work of the Society and its members. As Executive Officer, he revitalized the Society's meetings, instituted Mellon sabbatical fellowships in the humanities and social sciences, led the Society's gift support to record levels, created joint programs with scholarly societies in Sweden and the United Kingdom, oversaw the renovation of Philosophical Hall and the purchase of additional office space, launched a successful program of scientific exhibits, redefined the focus of the Society's publications and, not least, brought to these and all his dealings a warmth, grace and generosity of spirit which have enlivened and enriched the corporate life of the Society. In expressing its admiration and gratitude for Dr. Bearn's enlightened leadership, the Society also places on record its best wishes for a long and happy retirement and its anticipation of a long continuing association with him as one of the Society's most eminent members. It hereby awards to him its highest honor in recognition of his loyal and devoted service, and as a mark of the admiration, appreciation and affection of its members." Dr. Bearn was educated in England, and received his M.B., B.S. and M.D. degrees from the University of London. He came to the U.S. in 1951 for the first time to work at Rockefeller University for one year and soon embarked on the study of genetics of rare metabolic diseases. In 1964 he was named professor and senior physician. In 1966 Dr. Bearn was appointed professor and chairman of the department of medicine at Cornell University Medical College and physician-in-chief of New York Hospital. He established the first human genetics laboratory at the Medical College and with former Rockefeller colleagues initiated the joint M.D./Ph.D. program between the institutions. He remained at Cornell until 1979 when he was named senior vice-president for medical and scientific affairs of Merck, Sharpe & Dohme, International Division, a post he held until 1988. A frequent lecturer and author of numerous scientific articles, Dr. Bearn is also the author of Archibald Garrod and the Individuality of Man (Oxford, 1993), Sir Clifford Allbutt: Scholar and Physician (London, 2007), Sir Francis Richard Fraser; A Canny Scott Shapes British Medicine (Brighton, 2008). In 1970 Dr. Bearn joined the Rockefeller Board of Trustees and after serving for twenty-eight years, was elected emeritus trustee in 1998; he continues as a visiting professor and physician. In 2002 he received the David Rockefeller Award. Since 1987 Dr. Bearn has been a Trustee of the Howard Hughes Medical Institute and has also served as a trustee of the Helen Hay Whitney Foundation, the Josiah Macy, Jr. Foundation and as an overseer of the Jackson Laboratory. He became a member of the National Academy of Sciences in 1972 and is a member of its Institute of Medicine and numerous other academies and societies, including the Harvey Society (president 1972-73) and the American Society of Human Genetics (president, 1971). | |
| 4 | Name: | Dr. Richard John Bing | | | Institution: | Huntington Medical Research Institutes & University of Southern California | | | Year Elected: | 1995 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Deceased
| | | Birth Date: | 1909 | | | Death Date: | November 8, 2010 | | | | | | |
Richard J. Bing was born in Germany in 1909 and went on to become one of the great cardiologists of our time. In a career spanning more than sixty years, he pioneered the application of basic sciences to the study of the human heart. His early investigations were devoted to the mechanism of hypertension. He made seminal discoveries on the mechanism of congenital heart disease and of congestive heart failure by using physical and biochemical techniques and pioneered coincidence counting in the determination of coronary flow and in heart imaging. This work laid the foundation for modern PET scanning techniques. His investigation on cardiac metabolism showed that heart failure is related to possible defects in contractile proteins. Dr. Bing taught and conducted research at Johns Hopkins University and the University of Alabama and was chairman of medicine at Washington University's Veterans Administration Hospital. In 1959 he became chairman of the Department of Medicine at Wayne State University and in 1969 he was appointed professor of medicine at the University of Southern California. He joined Huntington Medical Research Institutes in 1969 to do biomedical research and also started the internal medicine residency program at Huntington Hospital. His major achievements there have included high-speed cinematography of coronary vessels and studies of the chemistry of the heart after a heart attack. Dr. Bing also followed a highly successful second career as a distinguished musician and composer. His chamber music has been performed by professional ensembles including the Chamber Players of the Los Angeles Philharmonic. His Mass had its premier performance by the Vienna Philharmonic at St. Stephen's Cathedral in Vienna in 1993. Richard John Bing died on November 8, 2010, at the age of 101, at his home in the Los Angeles-area community of La Canada Flintridge. | |
| 5 | Name: | Dr. Baruch S. Blumberg | | | Institution: | NASA Astrobiology Institute & Fox Chase Cancer Center & University of Pennsylvania | | | Year Elected: | 1986 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Deceased
| | | Birth Date: | 1925 | | | Death Date: | April 5, 2011 | | | | | | |
Baruch S. Blumberg served as the President of the American Philosophical Society 2005-2011. He was a Distinguished Scientist at Fox Chase Cancer Center and University Professor of Medicine and Anthropology at the University of Pennsylvania. From May 1999 until October 2002, he served as Director of the National Aeronautics and Space Administration (NASA) Astrobiology Institute headquartered at Ames Research Center (ARC). He was Senior Advisor to the Administrator of NASA (2000-01), and Principal Scientist of the NASA Division of Fundamental Space Biology (2002-04). In October 2008 he was appointed Distinguished Scientist at ARC associated with the NASA Lunar Science Institute and the Astrobiology Institute. He was Master of Balliol College, Oxford University, from 1989 to 1994 and, prior to that, Associate Director for Clinical Research at Fox Chase. He was on the staff of the National Institutes of Health from 1957 to 1964. Dr. Blumberg earned his M.D. from the College of Physicians and Surgeons, Columbia University, in 1951 and a Ph.D. in biochemistry from Oxford University in 1957.
Dr. Blumberg's research covered many areas including clinical research, epidemiology, virology, genetics, anthropology, and space-related biological science. He was awarded the Nobel Prize in Medicine in 1976 for "discoveries concerning new mechanisms for the origin and dissemination of infectious diseases" and specifically, for the discovery of the Hepatitis B virus. In 1993 he and his co-inventor, Dr. Irving Millman, were elected to the National Inventors Hall of Fame for their Hepatitis B vaccine and the diagnostic test for Hepatitis B. Dr. Blumberg was elected a member of the American Philosophical Society in 1986. He died April 5, 2011, at the age of 85, in Moffett Field, California. | |
| 6 | Name: | Dr. Emery N. Brown | | | Institution: | Massachusetts Institute of Technology; Harvard Medical School; Massachusetts General Hospital | | | Year Elected: | 2023 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Living
| | | Birth Date: | 1956 | | | | | | |
Emery N. Brown, M.D., Ph.D. was born and raised in Ocala, Florida. He attended Fessenden Elementary School, Osceola Junior High School and North Marion High School before graduating from the Phillips Exeter Academy in Exeter, New Hampshire. He spent the second semester of his senior year in Barcelona, Spain studying Spanish with the School Year Abroad Program.
Brown received his B.A. in Applied Mathematics (magna cum laude) from Harvard College. Before entering the Harvard M.D. Ph.D. Program, he spent a year studying mathematics as a Rotary Fellow at the Fourier Institute in Grenoble, France. Brown went on to earn his M.A. and Ph.D. in statistics from Harvard University and his M.D. (magna cum laude) from Harvard Medical School. He completed his internship in internal medicine at the Brigham and Women’s Hospital and his anesthesiology residency at MGH. After completing his residency in 1992, Brown joined the faculty at the MGH Department of Anesthesia and Harvard Medical School. In 2005, he also joined the faculty at MIT in the Department of Brain and Cognitive Sciences and the MIT and Harvard Health Sciences and Training Program.
Brown is presently the Edward Hood Taplin Profess of Medical Engineering and Computational Neuroscience at MIT; the Warren M. Zapol Professor of Anaesthesia at Harvard Medical School; and an anesthesiologist at MGH. He is an anesthesiologist-statistician whose research is defining the neuroscience of how anesthetics produce the states of general anesthesia. He also develops statistical methods for neuroscience data analysis.
In 2013 to 2014, Brown served on President Obama’s Brain Initiative Working Group. Currently, he serves on the Board of Trustees for the Simons Foundation and the Guggenheim Foundation.
Brown is a fellow of the American Institute for Medical and Biological Engineering, the IEEE, the American Statistical Association, the Institute of Mathematical Statistics, the American Academy of Arts and Sciences and the National Academy of Inventors. Brown is also a member of the National Academy of Medicine, the National Academy of Sciences, and the National Academy of Engineering.
Brown is the recipient of an NIH Director’s Pioneer Award, a Guggenheim Fellowship in Applied Mathematics, the American Society of Anesthesiologists Excellence in Research Award, the Dickson Prize in Science, the Swartz Prize for Theoretical and Computational Neuroscience, the Pierre Galletti Award, the Gruber Prize in Neuroscience and Doctorates of Science Honoris Causas from the University of Southern California and SUNY Downstate. | |
| 7 | Name: | Dr. William B. Castle | | | Institution: | Harvard University | | | Year Elected: | 1939 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Deceased
| | | Birth Date: | 1897 | | | Death Date: | 8/9/90 | | | | |
| 8 | Name: | Dr. Lowell Thelwell Coggeshall | | | Year Elected: | 1957 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Deceased
| | | Birth Date: | 1901 | | | Death Date: | 11/11/87 | | | | |
| 9 | Name: | Dr. Lawrence H. Einhorn | | | Institution: | Indiana University | | | Year Elected: | 2001 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Living
| | | Birth Date: | 1942 | | | | | | |
Lawrence Einhorn received his M.D. from the University of Iowa in 1968. He was a fellow in hematology/oncology at Indiana University Medical Center, 1971-72, and a fellow in oncology at the M.D. Anderson Hospital & Tumor Institute, 1972-73. He joined the Indiana University School of Medicine in 1973 where he has been a professor of medicine, clinical oncology and hematology and, since 1987, a Distinguished Professor of Medicine. In 2006 he became the first Lance Armstrong Foundation Professor of Oncology. Lawrence Einhorn achieved an international reputation as a young medical researcher who developed a very effective treatment for cancer of the testes. He is the Clinical Director of the Walther Oncology Center at the Indiana University Medical Center, where he has developed a talented team of investigators in oncology. His research has led to the improvement of treatment in a variety of cancers including the breast, bladder, lung and Hodgkin's Disease. He is well known among his peers in oncology and is well informed concerning the remarkable areas of research in his field. Solutions to cancer treatment and prevention will likely occur by teams of collaborators and institutions. Dr. Einhorn is well positioned to continue to make strong contributions in his important field. He is the recipient of many honors, including the Medal of Honor from the American Cancer Society (1983); the Gottlieb Award from M.D. Anderson Hospital (1986); the Bernard Schwartz Award from the Scripps Institute (1987); the Distinguished Clinician Award from the Milken Foundation (1989); the Kettering Prize for Cancer Research from General Motors Foundation (1992); the Presidential Medal of Honor from Indiana University (1996); the Jacquiatt Award in Oncology (1997); and the Vermeil Medal of Paris (2000). An active member of the American Society of Clinical Oncology, he served as its president, on the board of directors, and, for eight years, as editor of its Journal of Clinical Oncology. He was on the board of scientific counselors of the National Cancer Institute, where he was also an outstanding investigator grantee, 1985-92, 1993-2000. Dr. Einhorn was elected a member of the American Philosophical Society in 2001. | |
| 10 | Name: | Dr. Ronald M. Fairman | | | Institution: | Hospital of the University of Pennsylvania | | | Year Elected: | 2016 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Living
| | | Birth Date: | 1951 | | | | | | |
Ronald Fairman, an internationally acclaimed vascular surgeon, has played a central role in shaping an entirely new field of medicine, endovascular therapy. This field has virtually transformed and vastly improved the care of patients afflicted with blood vessel disorders such as aneurysms of the thoracic and abdominal aorta and blockage of arteries such as the carotid, renal and femoral. Fairman has been a pioneer in endovascular surgery. In this new treatment complex devices are inserted via catheters into peripheral arteries and with radiographic imaging advanced centrally to stent or seal off aortic aneurysms or to open and restore flow to narrowed or occluded arteries. Thus, intricate but less invasive procedures are substituted for major or more dangerous ones such as open operations to remove aneurysms or bypass arterial occlusions. Fairman’s research has developed, tested and improved endovascular procedures and the complex devices necessary for their conduct. Each new device must be subjected to extensive evaluation and clinical testing before it can be approved by the FDA. Approval can only be accomplished by demonstrated safety and effectiveness in well designed clinical trials. Fairman is at the forefront of these multi-institutional national trials, serving as the principal investigator, a major participant or advisor to the FDA on dozens of them.
Members may recall his presentation of this work to the Society at its April 2015 Meeting. The results of these trials and other aspects of his clinical experience has been reported by Fairman in more than 140 peer reviewed publications in scientific journals, dozens of chapters and editorials and in lectures and visiting professorships around the world. He is a member of the editorial boards of four vascular journals. In 2014 he received the highest award from the Society for Vascular Surgery and in 2016 he will serve as its president | |
| 11 | Name: | Dr. Judah Folkman | | | Institution: | Harvard Medical School & Children's Hospital | | | Year Elected: | 1999 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Deceased
| | | Birth Date: | 1933 | | | Death Date: | January 14, 2008 | | | | |
| 12 | Name: | Dr. Donald S. Fredrickson | | | Institution: | National Library of Medicine & National Institutes of Health & Howard Hughes Medical Institute | | | Year Elected: | 1985 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Deceased
| | | Birth Date: | 1924 | | | Death Date: | June 7, 2002 | | | | |
| 13 | Name: | Dr. A. McGehee Harvey | | | Institution: | Johns Hopkins University | | | Year Elected: | 1984 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Deceased
| | | Birth Date: | 1911 | | | Death Date: | 5/8/98 | | | | |
| 14 | Name: | Dr. Michael Heidelberger | | | Institution: | New York University | | | Year Elected: | 1968 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Deceased
| | | Birth Date: | 1888 | | | Death Date: | 6/25/91 | | | | |
| 15 | Name: | Dr. Charles B. Huggins | | | Institution: | University of Chicago | | | Year Elected: | 1962 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Deceased
| | | Birth Date: | 1901 | | | Death Date: | 1/12/97 | | | | |
| 16 | Name: | Dr. Yuet Wai Kan | | | Institution: | University of California, San Francisco | | | Year Elected: | 2009 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Living
| | | Birth Date: | 1936 | | | | | | |
Yuet Wai Kan is a graduate of the University of Hong Kong Medical School and is at present the Louis K. Diamond Professor of Hematology at the University of California, San Francisco. He has served on many organizations including as the President of the American Society of Hematology (1990) and currently as Chairman of the Croucher Foundation in Hong Kong that supports science and technology in Hong Kong. He works in the fields of hematology and genetics, and his research led to the innovation of DNA diagnosis that has found wide applications in many human conditions. In recognition of his contributions, he has been elected a member of learned science academies in the United States, Great Britain, Taiwan and China. He has received several honorary degrees and many national awards, including the Lasker Award for Medical Research (1991), international awards from Canada, Italy and Switzerland, and most recently the Shaw Prize in Life Sciences and Medicine from Hong Kong (2004). He was elected a member of the Institute of Medicine in 2011. | |
| 17 | Name: | Dr. John Nichols Loeb | | | Institution: | Columbia University | | | Year Elected: | 1998 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Living
| | | Birth Date: | 1935 | | | | | | |
John N. Loeb is Professor Emeritus of Medicine and Special Lecturer in Medicine at Columbia University. He graduated summa cum laude from both Harvard College and Harvard Medical School and after a year of internship at the Massachusetts General Hospital moved to New York City in 1962 for a year as an assistant resident on the Medical Service of the Presbyterian Hospital. After two years as a Research Associate with Gordon M. Tomkins in the Laboratory of Molecular Biology at the Institute of Arthritis and Metabolic Diseases at the National Institutes of Health, he returned to New York as Chief Resident in Medicine at the Presbyterian Hospital and Instructor in Medicine at the College of Physicians & Surgeons of Columbia University. He has remained affiliated with both institutions, where since 2005 he has been Professor Emeritus of Medicine and Special Lecturer in Medicine at Columbia University and continues as an Attending Physician at NewYork-Presbyterian Hospital. Dr. Loeb's research was principally focused on mechanisms of hormone action, the physical chemistry of receptor-ligand interactions and their quantitative relationship to biological response, and the regulation of glucose and monovalent cation transport. In pursuing these studies he chose to maintain only a small laboratory so that he could devote substantial time himself to benchwork, and his work was continuously funded by the National Institutes of Health from 1967 to 1999, support for the final ten years coming from an NIH MERIT award. From 1997 until 2003 he served as Associate Chairman for Research in the Department of Medicine and, from 2003 until his retirement, as Vice Chairman for Academic Affairs. Throughout his career Dr. Loeb has had an abiding interest in teaching both medical students and house staff, and in particular in bedside teaching. He has received numerous awards as a teacher at Columbia and additionally has devoted substantial time to teaching abroad. He received a Distinguished Service Award from the College of Physicians and Surgeons in 2007. Major non-scientific interests include nineteenth-century English and French literature and playing chamber music. Dr. Loeb was elected a member of the American Philosophical Society in 1998. | |
| 18 | Name: | Dr. Paul A. Marks | | | Institution: | Memorial Sloan-Kettering Cancer Center | | | Year Elected: | 2007 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Deceased
| | | Birth Date: | 1926 | | | Death Date: | April 28, 2020 | | | | | | |
Paul A. Marks was President Emeritus of Memorial Sloan-Kettering Cancer Center (MSKCC) and a member of the Sloan-Kettering Institute for Cancer Research. He was president and CEO of MSKCC from 1980-99. He received his A.B. and M.D. degrees from Columbia University and completed postdoctoral training at the National Institutes of Health, Bethesda, Maryland and the Pasteur Institute, Paris. Following his period at the Pasteur, Dr. Marks returned to Columbia College of Physicians and Surgeons as an assistant professor and was promoted to professor of medicine in 1967. In 1968 he was made professor of human genetics and Frode Jensen Professor of Medicine (1968-80) and the first chairman of the newly created Department of Human Genetics and Development. In 1970 he was elected Dean of the Faculty of Medicine (1970-73). In 1973 he became vice president of health sciences and director of the Comprehensive Cancer Center (1973-80) at Columbia University. In 1980 he was recruited to be the first president and CEO of the combined Memorial Hospital and Sloan-Kettering Institute. He retired from these positions in December 1999. Since January 2000 he has been a member of the Sloan-Kettering Institute, pursuing his research as head of the Laboratory of Cancer Cell Biology.
Dr. Marks published over 400 scientific articles in various scholarly journals. His research focused on the discovery and development of approaches to selectively arrest cancer cell growth. He and his colleagues identified a series of small molecules - hydroxamic acid based hybrid polar compounds - that inhibit histone deacetylases (HDAC), enzymes that play a role in regulating gene expression, cell growth, and cell death and can cause death of a variety of cancer cells, with little or no toxicity to normal cells. SAHA was approved by the Food and Drug Administration for the treatment of cutaneous T-cell lymphoma (CTCL) in October 2006. The first of these novel targeted histone deacetylase inhibitors to be approved for patient use. HDAC inhibitors represent a new approach to cancer therapy.
Dr. Marks was a member of the National Academy of Sciences and the Institute of Medicine and a fellow of the American Academy of Arts & Sciences. He served on many governmental and non-governmental committees and boards, including the President's Commission on Three Mile Island, the President's National Cancer Advisory Board, Councils of the National Academies and the boards of several academic institutions in the USA and abroad. He received a number of honors including the Distinguished Achievement Medal of Columbia University; the Japan Foundation for the Promotion of Cancer Research Medal; the Centenary Medal of the Pasteur Institute; honorary degrees from several universities, including his alma mater, Columbia University, the John Stearns Award for Lifetime Achievement in Medicine of the New York Academy of Medicine; and the President's National Medal of Science (USA). Dr. Marks was a founder of the biotechnology company Aton Pharma, Inc. that had an exclusive license from Columbia to develop SAHA as a cancer therapeutic, which is now a wholly owned subsidiary of Merck.
Paul A. Marks was elected a member of the American Philosophical Society in 2007. He died April 28, 2020 in New York, New York, at the age of 93. | |
| 19 | Name: | Dr. Francis D. Moore | | | Institution: | Harvard Medical School & Brigham & Women's Hospital | | | Year Elected: | 1998 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Deceased
| | | Birth Date: | 1913 | | | Death Date: | November 24, 2001 | | | | |
| 20 | Name: | Dr. David G. Nathan | | | Institution: | Dana-Farber Cancer Institute & Harvard Medical School | | | Year Elected: | 1999 | | | Class: | 2. Biological Sciences | | | Subdivision: | 204. Medicine, Surgery, Pathology and Immunology | | | Residency: | Resident | | | Living? : |
Living
| | | Birth Date: | 1929 | | | | | | |
David Nathan is one of the most distinguished pediatric hematologists in the country. He has spent his career at Harvard University, where he has been a professor of medicine and professor of pediatrics, and in 1985 he was appointed Pediatrician-in-Chief at Childrens Hospital in Boston. In 1995 he became President of the Dana-Farber Cancer Institute. Dr. Nathan has brought to his position scientific excellence, great integrity and a warm humanity. Among other awards he has received the National Medal of Science (1990) and the Henry Stratton Medal of the American Society of Hematology (1995). He earned his M.D. from Harvard Medical School in 1955. | |
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